Description

6-Benzyl-5,7-Dioxo-Hexahydropyrrolo[3,4-B]Pyridine is a high-purity, advanced pharmaceutical intermediate with a complex fused bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for Good Manufacturing Practice (GMP) production.
• Bioconjugation & Probe Development: The reactive carbonyl groups and nitrogen atoms provide handles for conjugation, useful in creating biochemical probes or targeted drug delivery systems.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in heterocyclic chemistry and new synthetic methodology development.

Basic Information

Product Name	6-Benzyl-5,7-Dioxo-Hexahydropyrrolo[3,4-B]Pyridine
CAS No.	1076198-93-0
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	6-Benzylhexahydro-5,7-dioxopyrrolo[3,4-b]pyridine; 6-Benzyl-2,3,3a,4,6,7-hexahydro-5H-pyrrolo[3,4-b]pyridine-5,7-dione; 6-Benzyl-5,7-dioxo-2,3,3a,4,6,7-hexahydro-1H-pyrrolo[3,4-b]pyridine; Pyrrolo[3,4-b]pyridine-5,7-dione, 6-benzylhexahydro-; 1076198-93-0; 6-Benzyl-5,7-dioxo-hexahydro-pyrrolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Benzyl-5,7-Dioxo-Hexahydropyrrolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and scale-up. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.