Description

1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate. Its value lies in its complex fused pyrazolopyridine scaffold, which is a privileged structure in medicinal chemistry for developing novel therapeutic agents. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries, particularly those focused on synthesizing new chemical entities for drug discovery programs targeting central nervous system and other disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile heterocyclic core.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for candidate drugs.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
CAS No.	1075729-10-0
Molecular Formula	C14H16ClN3
Molecular Weight	261.75 g/mol
Synonyms	1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine HCl; 1H-Pyrazolo[4,3-c]pyridine, 1-phenyl-4,5,6,7-tetrahydro-, hydrochloride; 1-Phenyl-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridine hydrochloride; 1-Phenyl-1,4,5,6,7,8-hexahydropyrazolo[4,3-c]pyridine hydrochloride; Pyrazolo[4,3-c]pyridine, 1-phenyl-4,5,6,7-tetrahydro-, monohydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.