Description

5-(tert-Butoxycarbonyl)-4,5,6,7-Tetrahydro-2-Methyl-1H-Pyrrolo[3,2-C]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrrolopyridine scaffold protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API (Active Pharmaceutical Ingredient) Development: Employed in the synthetic route development for potential new chemical entities (NCEs).
• Protease Inhibitor Synthesis: The pyrrolopyridine structure is relevant in the design of inhibitors for various enzymatic targets.
• Kinase Inhibitor Scaffold: Serves as a building block for compounds targeting kinase-related pathways in oncology and inflammation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity, protected intermediates.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)-4,5,6,7-Tetrahydro-2-Methyl-1H-Pyrrolo[3,2-C]Pyridine-3-Carboxylic Acid
CAS No.	1075257-98-5
Molecular Formula	C15H20N2O4
Molecular Weight	292.33 g/mol
Synonyms	2-Methyl-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-, 5-(1,1-dimethylethyl) ester; 5-Boc-4,5,6,7-tetrahydro-2-methyl-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid; 5-(tert-Butoxycarbonyl)-2-methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid; 5-Boc-2-methyl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid; tert-Butyl 2-methyl-3-carboxy-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate; CAS 1075257-98-5
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.