Description

Pyridine, 3,5-Difluoro-2-Nitro- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both nitro and fluorine substituents on the pyridine ring, makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for fluorinated active pharmaceutical ingredients (APIs) targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in coordination chemistry and catalysis, useful in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the creation of functionalized organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs), due to its electron-deficient aromatic system.
• Fluorinated Dye and Pigment Intermediate: Acts as a building block for synthesizing specialty dyes and pigments where fluorine substitution can alter color, lightfastness, and solubility properties.

Basic Information

Product Name	Pyridine, 3,5-Difluoro-2-Nitro-
CAS No.	1073634-13-5
Molecular Formula	C5H2F2N2O2
Molecular Weight	160.08 g/mol
Synonyms	3,5-Difluoro-2-nitropyridine; 2-Nitro-3,5-difluoropyridine; 3,5-Difluoro-2-nitro-pyridine; Pyridine, 3,5-difluoro-2-nitro-; 2-Nitro-3,5-difluoropyridine; 3,5-Difluoro-2-nitropyridine (CAS 1073634-13-5)
EINECS	Contact for details

Quality Control

Our Pyridine, 3,5-Difluoro-2-Nitro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.