Description

Methyl n-Boc-Thiazolidine-2-Carboxylate CAS NO 1073539-15-7 is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for the efficient and controlled introduction of the thiazolidine moiety, a key structural feature in many bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including peptide mimetics and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting metabolic and infectious diseases.
• Peptidomimetic Chemistry: Serves as a constrained, non-natural amino acid analog for constructing stable peptide backbones with enhanced bioavailability.
• Protease Inhibitor Development: Used in the research and production of inhibitors for various proteolytic enzymes.
• Chemical Biology & Probe Synthesis: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP and non-GMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Used in university and institutional labs for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	Methyl n-Boc-Thiazolidine-2-Carboxylate
CAS No.	1073539-15-7
Molecular Formula	C10H17NO4S
Molecular Weight	247.31 g/mol
Synonyms	Methyl (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-1,3-thiazolidine-2-carboxylate; Methyl 1-Boc-thiazolidine-2-carboxylate; 1-Boc-2-(methoxycarbonyl)thiazolidine; tert-Butyl 2-(methoxycarbonyl)thiazolidine-1-carboxylate; N-Boc-thiazolidine-2-carboxylic acid methyl ester; (S)-Methyl 1-(tert-butoxycarbonyl)thiazolidine-2-carboxylate; Boc-Thz-OMe; Thiazolidine-2-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl n-Boc-Thiazolidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.