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5-Chloro-3-Fluoro-2-(n-Propylamino)Pyridine,Hcl CAS NO 1073372-11-8


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CAS No.:1073372-11-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Chloro-3-Fluoro-2-(n-Propylamino)Pyridine,Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its utility as a key synthetic intermediate.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
  • Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
  • Material Science: Potential application as a monomer or functional additive in the synthesis of specialty polymers and advanced materials.
  • Ligand Synthesis: Can be utilized to develop novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 5-Chloro-3-Fluoro-2-(n-Propylamino)Pyridine,Hcl
CAS No. 1073372-11-8
Molecular Formula C9H13ClFN2•HCl
Molecular Weight 241.12 g/mol (Free base: 204.67 g/mol)
Synonyms 2-(Propylamino)-5-chloro-3-fluoropyridine hydrochloride; 5-Chloro-3-fluoro-N-propylpyridin-2-amine hydrochloride; 5-Chloro-3-fluoro-2-propylaminopyridine HCl; 2-Amino-5-chloro-3-fluoropyridine N-propyl hydrochloride; 1073372-11-8; 5-Chloro-3-fluoro-2-(propylamino)pyridine monohydrochloride
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Quality Control

Our 5-Chloro-3-Fluoro-2-(n-Propylamino)Pyridine,Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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