Description

5-Chloro-n-Cyclopropyl-3-Fluoropyridin-2-Amine, Hcl is a high-purity, halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate, enabling the construction of complex molecules for drug discovery and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate its unique cyclopropyl and halogen-substituted pyridine scaffold.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Chemical Biology Probe Synthesis: Employed in creating molecular tools and probes for studying enzyme function and biological pathways due to its ability to act as a hydrogen bond donor/acceptor.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, or functionalized polymers used in advanced materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects requiring this specific molecular architecture.

Basic Information

Product Name	5-Chloro-n-Cyclopropyl-3-Fluoropyridin-2-Amine, Hcl
CAS No.	1073372-09-4
Molecular Formula	C8H9Cl2FN2
Molecular Weight	223.08 g/mol
Synonyms	5-Chloro-N-cyclopropyl-3-fluoropyridin-2-amine hydrochloride; 2-Amino-5-chloro-N-cyclopropyl-3-fluoropyridine hydrochloride; 5-Chloro-3-fluoro-N-cyclopropylpyridin-2-amine HCl; 1073372-09-4; 5-Chloro-N-cyclopropyl-3-fluoro-2-pyridinamine hydrochloride; 2-Pyridinamine, 5-chloro-N-cyclopropyl-3-fluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 5-Chloro-n-Cyclopropyl-3-Fluoropyridin-2-Amine, Hcl is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.