Description

3-Methylpyridine-2-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing substituted pyridine or bipyridine motifs.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Serves as a versatile boronic ester partner in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) through efficient library synthesis.
• Catalyst & Ligand Development: Used to synthesize novel nitrogen-containing ligands for asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	3-Methylpyridine-2-Boronic Acid Pinacol Ester
CAS No.	1073371-84-2
Molecular Formula	C₁₂H₁₈BNO₂
Molecular Weight	219.09 g/mol
Synonyms	2-(3-Methylpyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methyl-2-pyridineboronic acid pinacol ester; 2-(3-Methyl-2-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methylpyridine-2-boronic acid neopentyl glycol ester (common name for pinacol type); 2-(3-Methylpyridyl)boronic acid pinacol ester; 3-Methyl-2-pyridylboronic acid pinacol ester; PINACOL 3-METHYLPYRIDIN-2-YLBORONATE
EINECS	Contact for details

Quality Control

Our 3-Methylpyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance in cGMP and ISO 9001 environments for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.