Description

2-Aminopyridine-3-Boronic Acid, Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing aminopyridine motifs.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Enables the synthesis of organic electronic materials, ligands for catalysis, and other functional organic compounds.
• Chemical Biology & Proteomics: Employed in the creation of molecular probes and inhibitors for studying biological pathways and protein function.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Process Chemistry: Valued for its stability (pinacol ester protection) in multi-step synthetic routes towards target molecules.

Basic Information

Product Name	2-Aminopyridine-3-Boronic Acid, Pinacol Ester
CAS No.	1073354-97-8
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 2-Amino-3-pyridineboronic acid pinacol ester; 2-Amino-3-(pinacolboryl)pyridine; Pinacol 2-Aminopyridine-3-boronate; 2-Aminopyridin-3-ylboronic acid pinacol ester; Boronic acid, B-(2-amino-3-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Aminopyridine-3-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) with full specification data are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.