Description

5-Bromo-2-Chloropyridine-3-Boronic Acid, Pinacol Ester is a high-value, multi-functional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of novel active ingredients and functional molecules. The CAS number for this product is 1073354-79-6.

Application

This versatile boronic ester is a key intermediate in the synthesis of complex organic molecules across several high-tech industries.

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, enabling the introduction of the pyridine core.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Used to construct organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored electronic properties.
• Chemical Biology Probes: Facilitates the synthesis of molecular probes for studying biological pathways and protein functions.
• Scale-up Process Development: Suitable for use in process chemistry from milligram to kilogram scale for pilot plant and commercial production.

Basic Information

Item	Details
Product Name	5-Bromo-2-Chloropyridine-3-Boronic Acid, Pinacol Ester
CAS No.	1073354-79-6
Molecular Formula	C11H14BBrClNO2
Molecular Weight	318.40 g/mol
Synonyms	5-Bromo-2-chloropyridine-3-boronic acid pinacol ester; (5-Bromo-2-chloropyridin-3-yl)boronic acid pinacol ester; 2-Chloro-5-bromopyridine-3-boronic acid pinacol ester; 3-Bromo-6-chloropyridine-2-boronic acid pinacol ester; 5-Bromo-2-chloro-3-pyridineboronic acid pinacol ester; Pinacol (5-Bromo-2-chloropyridin-3-yl)boronate; 1073354-79-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloropyridine-3-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency critical for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.