Description

2-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block featuring a pyridine core functionalized with a pyrrolidine and a pinacol boronate ester group. This compound matters as a critical intermediate in modern synthetic chemistry, enabling the construction of complex molecules through versatile cross-coupling reactions. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research organizations for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring complex heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive boronate handle.
• Catalyst Ligand Development: The pyridine-pyrrolidine motif can be utilized to develop novel ligands for transition metal catalysis.
• Academic & Contract Research: Essential reagent for methodology development and library synthesis in academic and CRO laboratory settings.

Basic Information

Item	Details
Product Name	2-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine
CAS No.	1073354-41-2
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-pyrrolidinyl)pyridine; 2-Pyrrolidin-1-yl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine; 2-(Pyrrolidin-1-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 2-(1-pyrrolidinyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1073354-41-2; 2-(1-Pyrrolidinyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidin-1-Yl)-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation of the boronate ester functionality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.