Description

5-Cyanopyridine-2-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & OLED Development: Serves as a precursor for creating functionalized pyridine-based ligands and organic semiconductors used in light-emitting diodes (OLEDs) and electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Ligand Synthesis for Catalysis: A versatile starting material for preparing sophisticated bidentate and tridentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Research: A critical reagent for custom synthesis organizations (CSOs) and R&D laboratories working on proprietary compound libraries and novel chemical entities.

Basic Information

Product Name	5-Cyanopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1073353-83-9
Molecular Formula	C₁₃H₁₅BN₂O₂
Molecular Weight	242.08 g/mol
Synonyms	2-(5-Cyanopyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Cyano-2-pyridineboronic acid pinacol ester; (5-Cyanopyridin-2-yl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-cyanopyridine; 5-CN-Py-2-Bpin; 5-Cyanopyridine-2-boronic acid neopentyl glycol ester (common alternative); 2-Pyridineboronic acid, 5-cyano-, 1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 5-Cyanopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure high purity and consistent performance in sensitive cross-coupling reactions. Certificates of Analysis (COA) with full analytical data are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.