Description

2-(3-Bromo-5-Ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds in complex molecule synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific bromo-ethoxy-phenyl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	2-(3-Bromo-5-Ethoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073339-03-3
Molecular Formula	C14H20BBrO3
Molecular Weight	327.02 g/mol
Synonyms	3-Bromo-5-ethoxyphenylboronic acid pinacol ester; (3-Bromo-5-ethoxyphenyl)boronic acid pinacol ester; 2-(3-Bromo-5-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-5-ethoxybenzeneboronic acid pinacol ester; Pinacol (3-bromo-5-ethoxyphenyl)boronate; B-3-Bromo-5-ethoxyphenylboronic acid pinacol ester; 1073339-03-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 2-(3-Bromo-5-Ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.