Description

2-(4-Bromo-3,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated aromatic frameworks.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Research: A versatile reagent for academic and industrial R&D in cross-coupling methodology development and library synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals and advanced intermediates for various high-value industries.

Basic Information

Product Name	2-(4-Bromo-3,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073338-97-2
Molecular Formula	C14H20BBrO2
Molecular Weight	311.02 g/mol
Synonyms	4-Bromo-3,5-dimethylbenzeneboronic acid pinacol ester; (4-Bromo-3,5-dimethylphenyl)boronic acid pinacol ester; 2-(4-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-3,5-dimethylphenylboronic acid pinacol ester; Pinacol (4-Bromo-3,5-dimethylphenyl)boronate; 4,4,5,5-Tetramethyl-2-(4-bromo-3,5-dimethylphenyl)-1,3,2-dioxaborolane; B-(4-Bromo-3,5-dimethylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-3,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.