Description

(R)-2-Amino-2-(5-Fluoropyridin-2-Yl)Ethanol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its defined stereochemistry and functional groups, which are essential for synthesizing targeted bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas requiring fluorinated pyridine motifs for enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug candidate properties.
• Fluorinated Compound Libraries: Serves as a building block for creating diverse screening libraries in drug discovery.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, fluorinated crop protection agents.
• Chemical Biology Probes: Useful for the synthesis of labeled compounds or probes for biological target identification.

Basic Information

Product Name	(R)-2-Amino-2-(5-Fluoropyridin-2-Yl)Ethanol
CAS No.	1073231-31-8
Molecular Formula	C7H9FN2O
Molecular Weight	156.16 g/mol
Synonyms	(R)-2-Amino-2-(5-Fluoro-2-pyridinyl)ethanol; (R)-2-(5-Fluoropyridin-2-yl)-2-aminoethanol; (R)-2-Amino-2-(5-fluoropyridin-2-yl)ethan-1-ol; (R)-5-Fluoro-2-(2-hydroxyethylamino)pyridine; (R)-1-(5-Fluoropyridin-2-yl)-2-aminoethanol; (R)-Enantiomer of 2-Amino-2-(5-fluoropyridin-2-yl)ethanol; 1073231-31-8; (R)-FPyAE
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-2-(5-Fluoropyridin-2-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.