Description

4-Amino-5-Chloronicotinic Acid Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its chloronicotinic acid backbone.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and organic synthesis projects in academic and industrial R&D labs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs where its functional groups are integral to the final molecule's activity.

Basic Information

Product Name	4-Amino-5-Chloronicotinic Acid Hydrochloride
CAS No.	1073182-98-5
Molecular Formula	C6H6ClN2O2•HCl
Molecular Weight	209.04 g/mol (Free base: 172.58 g/mol)
Synonyms	5-Chloro-4-aminonicotinic acid hydrochloride; 4-Amino-5-chloropyridine-3-carboxylic acid hydrochloride; 3-Pyridinecarboxylic acid, 4-amino-5-chloro-, hydrochloride (1:1); 4-Amino-5-chloro-3-pyridinecarboxylic acid hydrochloride; 1073182-98-5; 4-Amino-5-chloronicotinic acid HCl
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloronicotinic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.