Description

Methyl 3-Amino-6-Chloro-2-Methylisonicotinate CAS NO 1073182-63-4 is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its chlorinated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential building block for functionalized ligands in catalysis or for creating specialty polymers with tailored properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Methyl 3-Amino-6-Chloro-2-Methylisonicotinate
CAS No.	1073182-63-4
Molecular Formula	C9H11ClN2O2
Molecular Weight	214.65 g/mol
Synonyms	Methyl 3-Amino-6-chloro-2-picolinate; 6-Chloro-3-amino-2-picolinic acid methyl ester; 3-Amino-6-chloro-2-methylisonicotinic acid methyl ester; 2-Pyridinecarboxylic acid, 3-amino-6-chloro-2-methyl-, methyl ester; Methyl 3-amino-6-chloro-2-methylpyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-6-Chloro-2-Methylisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.