Description

2-Bromo-5-Chloropyridine-4-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules. Its specific substitution pattern offers precise control over molecular architecture in target-oriented synthesis.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and tool compounds for target identification and validation.
• Ligand & Catalyst Development: Utilized to construct sophisticated chelating ligands and organometallic catalysts for asymmetric synthesis.
• Custom Synthesis & Contract Research: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2-Bromo-5-Chloropyridine-4-Boronic Acid
CAS No.	1072952-51-2
Molecular Formula	C5H4BBrClNO2
Molecular Weight	236.26 g/mol
Synonyms	(2-Bromo-5-chloropyridin-4-yl)boronic acid; 2-Bromo-5-chloro-4-pyridineboronic acid; 4-Borono-2-bromo-5-chloropyridine; 2-Bromo-5-chloro-4-pyridinylboronic acid; B-(2-Bromo-5-chloro-4-pyridinyl)boronic acid; 1072952-51-2; 2-Bromo-5-chloropyridine-4-boronic acid pinacol ester (common derivative).
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloropyridine-4-Boronic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation (by 1H NMR and IR), and impurity profile is supplied with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider keeping the container under an inert atmosphere (argon or nitrogen) in a freezer (-20°C) to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.