Description

2-Picoline-5-Boronic Acid Hydrate is a versatile organoboron building block, specifically a pyridine-substituted boronic acid derivative. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, catalyst development, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and material science.
• Organic Electronic Materials: Employed in the research and development of organic light-emitting diodes (OLEDs) and other electronic materials requiring precise molecular architecture.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compound libraries.
• Custom Synthesis: Provides a starting point for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke fine chemicals for clients.

Basic Information

Product Name	2-Picoline-5-Boronic Acid Hydrate
CAS No.	1072952-30-7
Molecular Formula	C6H8BNO2 · xH2O
Molecular Weight	136.95 (Anhydrous Basis)
Synonyms	(5-Methylpyridin-2-yl)boronic acid hydrate; 5-Methyl-2-pyridineboronic acid hydrate; 2-(5-Methylpyridyl)boronic acid hydrate; 5-Methyl-2-pyridinylboronic acid hydrate; 2-Pyridineboronic acid, 5-methyl-, hydrate; 5-Methylpyridine-2-boronic acid hydrate
EINECS	Contact for details

Quality Control

Our 2-Picoline-5-Boronic Acid Hydrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.