Description

6-Chloro-2-Methoxypyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by constructing complex heterocyclic scaffolds with specific biological activity.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and inhibitors for studying enzyme function and protein-protein interactions.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyridine-based ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	6-Chloro-2-Methoxypyridine-3-Boronic Acid
CAS No.	1072946-50-9
Molecular Formula	C6H7BClNO3
Molecular Weight	187.39 g/mol
Synonyms	(6-Chloro-2-methoxypyridin-3-yl)boronic acid; 3-Borono-6-chloro-2-methoxypyridine; 6-Chloro-2-methoxy-3-pyridineboronic acid; 6-Chloro-2-methoxypyridine-3-boronic acid pinacol ester (common derivative); 2-Methoxy-6-chloropyridine-3-boronic acid; 1072946-50-9; 3-Pyridineboronic acid, 6-chloro-2-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2-Methoxypyridine-3-Boronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for advanced synthetic applications. Our quality commitment includes comprehensive identity, purity, and impurity profile verification. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.