Description

Lithium Hydrogen-5-Methylpyridine-2-Boronate is a specialized organoboron reagent featuring a pyridine-boronate complex. This compound matters as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon and carbon-heteroatom bond formations. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in cross-coupling and Suzuki-Miyaura reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Development: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a monomer or functionalization agent in the development of novel organic electronic materials and polymers.
• Catalyst Ligand Preparation: Utilized for the synthesis of sophisticated ligand systems in homogeneous catalysis.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.
• Chemical Library Production: Employed in combinatorial chemistry for the rapid generation of diverse compound libraries for screening.

Basic Information

Product Name	Lithium Hydrogen-5-Methylpyridine-2-Boronate
CAS No.	1072946-48-5
Molecular Formula	C6H7BBLiNO2
Molecular Weight	146.89 g/mol
Synonyms	5-Methylpyridine-2-boronic acid, lithium salt; 2-Borono-5-methylpyridine, lithium derivative; Lithium 5-methylpyridin-2-ylboronate; 5-Methyl-2-pyridineboronic acid lithium salt; (5-Methylpyridin-2-yl)boronic acid lithium salt; Lithium (5-methyl-2-pyridinyl)boronate; Boronic acid, B-(5-methyl-2-pyridinyl)-, lithium salt
EINECS	Contact for details

Quality Control

Our Lithium Hydrogen-5-Methylpyridine-2-Boronate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.