Description

(2-Methylcarboxy)Pyridine-5-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing pyridine and biphenyl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a building block for constructing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Methylcarboxy)Pyridine-5-Boronic Acid
CAS No.	1072945-86-8
Molecular Formula	C8H10BNO4
Molecular Weight	194.98 g/mol
Synonyms	5-Borono-2-pyridinecarboxylic acid, methyl ester; Methyl 5-boronopicolinate; 2-(Methoxycarbonyl)pyridine-5-boronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic acid methyl ester (Pinacol ester precursor); Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 2-Carbomethoxypyridine-5-boronic acid; Picolinic acid, 5-borono-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of (2-Methylcarboxy)Pyridine-5-Boronic Acid is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.