Description

2-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester is a high-value, protected boronic acid ester building block essential for modern synthetic chemistry. This compound matters because it provides a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical researchers, and specialty chemical manufacturers for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyridine and bipyridine scaffolds.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boron reagent for palladium-catalyzed carbon-carbon bond formation to create complex heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heteroaromatic motifs.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and organic photovoltaics, where conjugated structures are critical.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	2-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester
CAS No.	1072944-99-0
Molecular Formula	C₁₇H₂₇BN₂O₄
Molecular Weight	334.22 g/mol
Synonyms	2-((tert-Butoxycarbonyl)amino)pyridine-3-boronic acid pinacol ester; 2-Boc-aminopyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine, N-Boc-protected; Boc-2-amino-3-pyridylboronic acid pinacol ester; 2-(Boc-amino)-3-pyridylboronic acid pinacol ester; 2-(tert-Butoxycarbonylamino)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-tert-Butyloxycarbonylaminopyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.