Description

2-Chloro-3-Bromo-4-Pyridineboronic Acid is a highly functionalized heterocyclic boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its ability to participate in key cross-coupling reactions, enabling the efficient construction of complex pharmaceutical intermediates and advanced materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct complex pyridine-based molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) and components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in biochemical assay development and diagnostic research.
• Catalyst Ligand Development: Utilized in the synthesis of novel bidentate or tridentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-3-Bromo-4-Pyridineboronic Acid
CAS No.	1072944-16-1
Molecular Formula	C5H4BBrClNO2
Molecular Weight	236.26 g/mol
Synonyms	(2-Chloro-3-bromopyridin-4-yl)boronic acid; 2-Chloro-3-bromo-4-pyridinylboronic acid; 4-Borono-2-chloro-3-bromopyridine; 2-Chloro-3-bromo-4-pyridineboronic acid pinacol ester (common derivative); 1072944-16-1; 2-Cl-3-Br-4-PyB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Bromo-4-Pyridineboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.