Description

5-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where precision and reliability in synthesis are paramount.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific pyrazole-boronate structures.
• Material Science Research: Building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Catalyst Ligand Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	5-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1072709-32-0
Molecular Formula	C15H25BN2O3
Molecular Weight	292.19 g/mol
Synonyms	5-Methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1H-Pyrazole, 5-methyl-1-(tetrahydro-2H-pyran-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole; THP-Protected Pyrazole Boronic Ester; 5-Methyl-1-THP-4-(pinacol boronate)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-(Tetrahydro-2H-Pyran-2-Yl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.