Description

Methyl 3-Amino-5-Bromopicolinate CAS NO 1072448-08-8 is a high-purity, versatile brominated picolinate derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a reactive amino group and a bromine substituent on the pyridine ring, enabling precise chemical modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity brominated heterocycles.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and for creating compound libraries for screening.

Basic Information

Product Name	Methyl 3-Amino-5-Bromopicolinate
CAS No.	1072448-08-8
Molecular Formula	C7H7BrN2O2
Molecular Weight	231.05 g/mol
Synonyms	Methyl 3-Amino-5-Bromopyridine-2-carboxylate; 5-Bromo-3-aminopicolinic Acid Methyl Ester; 3-Amino-5-bromo-2-pyridinecarboxylic Acid Methyl Ester; Methyl 5-Bromo-3-aminopicolinate; 2-Pyridinecarboxylic acid, 3-amino-5-bromo-, methyl ester; Methyl 3-amino-5-bromopyridine-2-carboxylate; 3-Amino-5-bromopicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Bromopicolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.