Description

Methyl 3-Fluoro-5-Hydroxybenzoate is a high-purity fluorinated aromatic ester, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic scaffolds to modulate bioavailability, metabolic stability, and receptor binding.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated components for electronic display materials and organic light-emitting diodes.
• Polymer Modification: Intermediate for introducing fluorinated benzoate groups into polymer chains to alter thermal stability, chemical resistance, and surface properties.
• Chemical Research: Valuable reagent in academic and industrial laboratories for exploring new fluorination reactions and synthesizing novel aromatic compounds.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name	Methyl 3-Fluoro-5-Hydroxybenzoate
CAS No.	1072004-32-0
Molecular Formula	C8H7FO3
Molecular Weight	170.14 g/mol
Synonyms	3-Fluoro-5-hydroxybenzoic acid methyl ester; Methyl 3-fluoro-5-hydroxybenzoate; Benzoic acid, 3-fluoro-5-hydroxy-, methyl ester; 5-Hydroxy-3-fluorobenzoic acid methyl ester; 3-Fluoro-5-methoxycarbonylphenol
EINECS	Contact for details

Quality Control

Our Methyl 3-Fluoro-5-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.