Description

5-(Pyridin-3-Yl)-1H-Pyrazol-3-Amine Hydrochloride is a high-purity organic salt, specifically a hydrochloride derivative of a pyrazolylpyridine amine, serving as a critical pharmaceutical intermediate and research chemical. Its value lies in its role as a versatile building block for synthesizing complex molecules, particularly in medicinal chemistry for the development of new therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Organic Synthesis: Acts as a versatile reagent for constructing complex nitrogen-containing heterocycles in academic and industrial R&D.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	5-(Pyridin-3-Yl)-1H-Pyrazol-3-Amine Hydrochloride
CAS No.	1071623-05-6
Molecular Formula	C8H9N4·HCl
Molecular Weight	196.64 g/mol (Free base: 160.18 g/mol)
Synonyms	3-Amino-5-(3-pyridinyl)-1H-pyrazole hydrochloride; 5-(3-Pyridyl)-1H-pyrazol-3-amine hydrochloride; 1H-Pyrazol-3-amine, 5-(3-pyridinyl)-, hydrochloride; 5-(Pyridin-3-yl)-1H-pyrazol-3-amine HCl; 3-Pyridylpyrazole-3-amine hydrochloride; 5-(3-Pyridinyl)-3-amino-1H-pyrazole hydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Pyridin-3-Yl)-1H-Pyrazol-3-Amine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.