Description

7-Chloro-2-(trimethylsilyl)furo[3,2-b]pyridine is a high-value, organosilicon-substituted heterocyclic compound that serves as a critical synthetic intermediate. Its unique fused-ring structure, featuring both a halogen and a silyl protecting group, makes it a versatile building block for advanced chemical synthesis. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated heterocyclic core.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The chloro and trimethylsilyl groups make it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Serves as a starting material for the preparation of novel nitrogen-containing ligands for catalysis.
• Chemical Biology Probes: Used to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	7-Chloro-2-(Trimethylsilyl)Furo[3,2-B]Pyridine
CAS No.	1071540-51-6
Molecular Formula	C₁₀H₁₂ClNOSi
Molecular Weight	241.74 g/mol
Synonyms	7-Chloro-2-(trimethylsilyl)furo[3,2-b]pyridine; 2-(Trimethylsilyl)-7-chlorofuro[3,2-b]pyridine; Furo[3,2-b]pyridine, 7-chloro-2-(trimethylsilyl)-; 7-Chloro-2-trimethylsilylfuro[3,2-b]pyridine; CAS 1071540-51-6
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(trimethylsilyl)furo[3,2-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up activities with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.