Description

(2R,3R)-1-Ethyl-6-Oxo-2-Phenylpiperidine-3-Carboxylic Acid is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chiral building block for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and analgesic research.
• Chiral Building Block: Used in asymmetric synthesis to introduce the (2R,3R) stereochemistry into complex molecular architectures.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodological studies in heterocyclic and piperidine chemistry.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2R,3R)-1-Ethyl-6-Oxo-2-Phenylpiperidine-3-Carboxylic Acid
CAS No.	1071536-01-0
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	1-Ethyl-6-oxo-2-phenylpiperidine-3-carboxylic acid, (2R,3R)-; (2R,3R)-1-Ethyl-2-phenyl-6-oxopiperidine-3-carboxylic acid; (2R,3R)-2-Phenyl-1-ethyl-6-oxopiperidine-3-carboxylic acid; (2R,3R)-rel-1-Ethyl-6-oxo-2-phenyl-3-piperidinecarboxylic acid; 1-Ethyl-2-phenyl-6-oxopiperidine-3-carboxylic acid (racemic mixture); 1071536-01-0; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (2R,3R)-1-Ethyl-6-Oxo-2-Phenylpiperidine-3-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.