Description

(S)-2-Amino-2-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol is a high-value, chiral amino alcohol building block featuring a trifluoromethyl-substituted pyridine core. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its defined stereochemistry and fluorine atoms impart desirable biological activity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients. CAS No. 1071435-66-9.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of small molecule drugs, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Building block for novel pesticides and herbicides, leveraging the trifluoromethyl group for enhanced lipophilicity and target binding.
• Ligand & Catalyst Development: Used in asymmetric synthesis as a precursor for chiral ligands and organocatalysts.
• Chemical Biology Research: Probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Advanced Material Precursor: Potential monomer or functionalizing agent for specialty polymers with unique surface properties.

Basic Information

Product Name	(S)-2-Amino-2-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol
CAS No.	1071435-66-9
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	(S)-2-Amino-2-(6-(trifluoromethyl)pyridin-3-yl)ethan-1-ol; (S)-2-Amino-2-(6-(trifluoromethyl)-3-pyridyl)ethanol; (S)-1-(6-(Trifluoromethyl)pyridin-3-yl)-2-aminoethanol; (S)-α-Amino-6-(trifluoromethyl)nicotinemethanol; 1071435-66-9; (S)-2-Amino-2-(6-trifluoromethyl-3-pyridyl)ethanol; (S)-2-(6-(Trifluoromethyl)pyridin-3-yl)-2-aminoethanol
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-2-(6-(Trifluoromethyl)Pyridin-3-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.