Description

Neuraminic Acid,n-Acetyl-2-S-(4-Methylphenyl)-2-Thio-,Menthyl Ester, 4,7,8,9-Tetraacetate is a sophisticated, multi-functionalized derivative of neuraminic acid, a key structural motif in sialic acid chemistry. This compound is engineered to serve as a crucial advanced synthetic intermediate for the development of novel bioactive molecules and research tools. It is primarily targeted at pharmaceutical R&D and academic research laboratories focused on glycobiology, antiviral drug discovery, and the synthesis of complex carbohydrate mimetics.

Application

• Key Intermediate in Antiviral Drug Discovery: Used in the synthesis of sialidase (neuraminidase) inhibitors for research into influenza and other viral infections.
• Glycobiology Research: Serves as a building block for creating sialic acid analogs to study cell surface recognition, signaling, and immune response modulation.
• Medicinal Chemistry: A versatile precursor for the development of novel therapeutic agents targeting carbohydrate-protein interactions.
• Chemical Biology Probe Development: Utilized to create labeled or modified sialic acid derivatives for imaging and mechanistic studies.
• Process Chemistry & Scale-up: Employed in route development and optimization for the production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Neuraminic Acid,n-Acetyl-2-S-(4-Methylphenyl)-2-Thio-,Menthyl Ester, 4,7,8,9-Tetraacetate
CAS No.	1071226-27-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4,7,8,9-Tetra-O-acetyl-2-S-(4-methylphenyl)-2-thio-N-acetylneuraminic acid menthyl ester; N-Acetyl-2-S-(p-tolyl)-2-thioneuraminic Acid Menthyl Ester Tetraacetate; Sialic Acid C-2 Thioaryl Derivative; Advanced Sialic Acid Intermediate; Neu5Ac2SPhMe Menthyl Ester Tetraacetate
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity for sensitive research applications. Our quality assurance includes comprehensive analytical characterization using HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.