Description

2-Amino-3-Chloro-5-Iodo-Benzoic Acid Methyl Ester is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique substitution pattern, which makes it a critical intermediate in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting specific receptors or requiring halogenated motifs for bioactivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the iodine and chlorine substituents can influence biological activity and environmental persistence.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with tailored electronic or optical properties.
• Chemical Synthesis: Versatile building block for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization due to the presence of reactive amino, ester, and halogen groups.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for metal catalysis and organocatalysts.
• Diagnostic Agent Precursor: Potential intermediate in the synthesis of contrast agents or radiolabeled compounds for medical imaging, leveraging the iodine atom.

Basic Information

Product Name	2-Amino-3-Chloro-5-Iodo-Benzoic Acid Methyl Ester
CAS No.	1070977-94-4
Molecular Formula	C8H7ClINO2
Molecular Weight	311.51 g/mol
Synonyms	Methyl 2-Amino-3-Chloro-5-Iodobenzoate; Benzoic acid, 2-amino-3-chloro-5-iodo-, methyl ester; 3-Chloro-5-iodoanthranilic acid methyl ester; Methyl 3-chloro-5-iodoanthranilate; 2-Amino-3-chloro-5-iodobenzoic acid methyl ester; Methyl 2-amino-3-chloro-5-iodobenzoate
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.