Description

4-Chloro-2-Fluoro-5-Nitro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique halogenated and nitrated benzoate structure makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its nitro and halogen substituents for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex colorants and photographic chemicals due to its reactive ester and nitro groups.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for constructing biaryl systems.
• Laboratory Scale Development: Utilized in academic and industrial R&D for method development and scale-up studies of novel synthetic pathways.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-Nitro-Benzoic Acid Methyl Ester
CAS No.	1070893-15-0
Molecular Formula	C8H5ClFNO4
Molecular Weight	233.58 g/mol
Synonyms	Methyl 4-Chloro-2-fluoro-5-nitrobenzoate; Benzoic acid, 4-chloro-2-fluoro-5-nitro-, methyl ester; 4-Chloro-2-fluoro-5-nitrobenzoic acid methyl ester; Methyl 4-chloro-2-fluoro-5-nitrobenzoate; 1070893-15-0; 4-Chloro-2-fluoro-5-nitro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Fluoro-5-Nitro-Benzoic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.