Description

3-Bromo-5-Chloro-4-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern offers versatile reactivity for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen atoms for further cross-coupling or substitution reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogen handles for structural diversification.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromine and iodine atoms.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring new synthetic routes and structure-activity relationships.
• Ligand Synthesis: Used to prepare complex polydentate ligands for coordination chemistry and catalysis.

Basic Information

Item	Details
Product Name	3-Bromo-5-Chloro-4-Iodopyridine
CAS No.	1070870-39-1
Molecular Formula	C5H2BrClIN
Molecular Weight	318.34 g/mol
Synonyms	4-Iodo-3-bromo-5-chloropyridine; 5-Chloro-3-bromo-4-iodopyridine; 3-Bromo-5-chloro-4-iodopyridine; Pyridine, 3-bromo-5-chloro-4-iodo-; 1070870-39-1; 4-Iodo-5-chloro-3-bromopyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-4-Iodopyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.