Description

Cy3 Se(Mono So3) CAS NO 1068148-46-8 is a sulfonated derivative of the Cyanine 3 (Cy3) fluorophore, engineered for enhanced water solubility and reduced aggregation in aqueous environments. This modification is critical for achieving consistent, high-fidelity labeling in sensitive biological assays where non-specific binding can compromise data integrity. It is an essential reagent for researchers and manufacturers in the fields of molecular diagnostics, flow cytometry, and next-generation sequencing who require superior photostability and conjugation efficiency for their probe and antibody development.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to antibodies, proteins, peptides, and oligonucleotides for use in immunoassays (ELISA, Western Blot) and in situ hybridization (FISH).
• Flow Cytometry & Cell Sorting: Cell surface and intracellular staining for immunophenotyping and functional analysis of cell populations.
• Microarray & Biochip Fabrication: Preparation of fluorescent probes for genomic and proteomic screening platforms.
• Next-Generation Sequencing (NGS): Labeling for detection in certain sequencing-by-synthesis or single-molecule imaging applications.
• Microscopy & Imaging: Used in confocal, super-resolution, and live-cell imaging due to its bright emission and compatibility with standard Cy3 filter sets.
• Diagnostic Kit Development: A key component in the manufacture of lateral flow assays and other point-of-care diagnostic devices.
• Pharmaceutical Research: Tracking and visualization of drug delivery systems and cellular uptake mechanisms.

Basic Information

Product Name	Cy3 Se(Mono So3) CAS NO 1068148-46-8
CAS No.	1068148-46-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sulfo-Cyanine3 SE; Cy3™ Mono Succinimidyl Ester, Sulfonated; Sulfo-Cy3 NHS Ester; 1-(6-((2,5-Dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3,3-dimethyl-2-((E)-3-((E)-1-(3-sulfopropyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-3H-indol-1-ium; Cy3 Mono Sulfonated NHS Ester; Water-soluble Cy3 NHS ester; Sulfo-Cy3 SE
EINECS	Contact for details

Quality Control

Every batch of Cy3 Se(Mono So3) is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and functional performance data is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Extinction Coefficient	~150,000 cm⁻¹M⁻¹ (at λmax)
Functional Performance	Conforms to reference standard in labeling efficiency test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.