Description

2-Bromo-3-(Thiazol-2-Yloxy)-Pyridine is a high-purity (98+%) heterocyclic organic compound with the molecular formula C8H5BrN2OS and a molecular weight of 257.11. This specialized intermediate is valued for its unique molecular architecture, which combines pyridine and thiazole moieties linked by an ether bridge, making it a versatile building block for advanced chemical synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active molecules. The compound, CAS 1065484-74-3, is supplied with rigorous quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and ligands for catalytic systems.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex heterocyclic systems.
• Academic & R&D: Utilized in university and corporate research laboratories for method development and exploring new chemical spaces.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-3-(Thiazol-2-Yloxy)-Pyridine
CAS No.	1065484-74-3
Molecular Formula	C8H5BrN2OS
Molecular Weight	257.11 g/mol
Synonyms	2-Bromo-3-(2-thiazolyloxy)pyridine; 3-(Thiazol-2-yloxy)-2-bromopyridine; Pyridine, 2-bromo-3-(2-thiazolyloxy)-; 2-Bromo-3-(thiazol-2-yloxy)pyridine; 2-Bromo-3-(thiazol-2-yloxy)pyridine; 2-Bromo-3-(thiazol-2-yloxy)pyridine; 1065484-74-3; 2-Bromo-3-(thiazol-2-yloxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-(Thiazol-2-Yloxy)-Pyridine is produced and tested under a strict quality management system. We guarantee a minimum purity of 98%, verified by advanced analytical techniques including HPLC and NMR spectroscopy. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to ensure full traceability and compliance with your internal quality standards and research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.