Description

4-(2-Bromo-Pyridin-3-Yloxy)-6-Chloro-Pyrimidine is a high-purity (98+%) halogenated heterocyclic building block with the molecular formula C9H5BrClN3O and a molecular weight of 286.52. This compound is a critical intermediate for the synthesis of complex molecules, offering precise reactivity for constructing advanced chemical architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

This versatile pyrimidine-pyridine hybrid serves as a key synthetic intermediate in several high-value research and development areas:

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by acting as a scaffold for bioactive molecules.
• Material Science: Serves as a precursor for creating specialized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in designing molecular probes and activity-based probes (ABPs) for target identification and validation.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-(2-Bromo-Pyridin-3-Yloxy)-6-Chloro-Pyrimidine
CAS No.	1065484-68-5
Molecular Formula	C9H5BrClN3O
Molecular Weight	286.52 g/mol
Synonyms	6-Chloro-4-[(2-bromopyridin-3-yl)oxy]pyrimidine; 4-(2-Bromo-3-pyridyloxy)-6-chloropyrimidine; 4-(2-Bromopyridin-3-yloxy)-6-chloropyrimidine; 6-Chloro-4-(2-bromopyridin-3-yloxy)pyrimidine; 3-((6-Chloropyrimidin-4-yl)oxy)-2-bromopyridine; 2-Bromo-3-((6-chloropyrimidin-4-yl)oxy)pyridine
EINECS	Contact for details

Quality Control

Our 4-(2-Bromo-Pyridin-3-Yloxy)-6-Chloro-Pyrimidine is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified 98+% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.