Description

2-(2-Bromopyridin-3-Yloxy)-5-(Chloromethyl)Pyridine, 98+% C11H8BrClN2O, Mw: 299.56 is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites—the bromopyridine and chloromethyl groups—which enable selective cross-coupling and functionalization reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Nucleophilic Substitution: The chloromethyl group allows for further alkylation or introduction of various functional groups.

Basic Information

Product Name	2-(2-Bromopyridin-3-Yloxy)-5-(Chloromethyl)Pyridine
CAS No.	1065484-66-3
Molecular Formula	C11H8BrClN2O
Molecular Weight	299.56 g/mol
Synonyms	5-(Chloromethyl)-2-[(2-bromopyridin-3-yl)oxy]pyridine; 2-(2-Bromo-3-pyridyloxy)-5-(chloromethyl)pyridine; 3-[[5-(Chloromethyl)-2-pyridinyl]oxy]-2-bromopyridine; 2-Bromo-3-((5-(chloromethyl)pyridin-2-yl)oxy)pyridine; 1065484-66-3; Bromopyridine Chloromethylpyridine Ether; BCPE Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromopyridin-3-Yloxy)-5-(Chloromethyl)Pyridine is manufactured and tested under a strict quality management system. We guarantee a minimum purity of 98+%, verified by advanced analytical techniques including HPLC and NMR. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.