Description

3-[(6-Bromo-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) advanced pharmaceutical intermediate with the molecular formula C16H24BrN3O2 and a molecular weight of 370.29. This compound is a critical building block for medicinal chemistry research and the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile piperidine-pyridine scaffold for drug discovery. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its functionalized piperidine and bromopyridine moieties.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for complex target molecules.
• Agrochemical Development: Potential intermediate for creating new crop protection agents and pesticides.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis or metal-organic frameworks.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	3-[(6-Bromo-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1065484-38-9
Molecular Formula	C16H24BrN3O2
Molecular Weight	370.29 g/mol
Synonyms	tert-Butyl 3-[[(6-bromo-2-pyridinyl)amino]methyl]-1-piperidinecarboxylate; 1-Boc-3-[(6-bromo-pyridin-2-ylamino)-methyl]piperidine; 1-(tert-Butoxycarbonyl)-3-[(6-bromopyridin-2-ylamino)methyl]piperidine; N-(6-Bromopyridin-2-yl)-N-(1-Boc-piperidin-3-ylmethyl)amine; 3-((6-Bromopyridin-2-ylamino)methyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 3-[(6-Bromo-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines as required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.