Description

3-(3-Nitro-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C16H23N3O5 and a molecular weight of 337.38. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of complex heterocyclic compounds, particularly those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing piperidine and nitro-pyridine pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a critical building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme inhibition and receptor binding.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and novel heterocycle formation.

Basic Information

Product Name	3-(3-Nitro-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1065484-08-3
Molecular Formula	C16H23N3O5
Molecular Weight	337.38 g/mol
Synonyms	1-Boc-3-((3-nitropyridin-2-yloxy)methyl)piperidine; tert-Butyl 3-(((3-nitropyridin-2-yl)oxy)methyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-((3-nitropyridin-2-yloxy)methyl)piperidine; 3-[(3-Nitro-2-pyridinyloxy)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 2-((1-Boc-piperidin-3-yl)methoxy)-3-nitropyridine; 3-((3-Nitropyridin-2-yloxy)methyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-(3-Nitro-Pyridin-2-Yloxymethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and identity criteria. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. For long-term storage, consider using desiccants and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.