Description

tert-Butyl 4-(3-nitropyridin-2-yloxy)piperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a nitropyridine and a Boc-protected piperidine scaffold. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel drug candidates targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for candidate drugs under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Employed in the construction of molecular probes to study enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development pipelines.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(3-nitropyridin-2-yloxy)piperidine-1-carboxylate
CAS No.	1065484-06-1
Molecular Formula	C15H21N3O5
Molecular Weight	323.35 g/mol
Synonyms	1-Boc-4-[(3-nitropyridin-2-yl)oxy]piperidine; 1-(tert-Butoxycarbonyl)-4-[(3-nitropyridin-2-yl)oxy]piperidine; 4-(3-Nitro-2-pyridyloxy)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-((3-nitropyridin-2-yl)oxy)piperidine-1-carboxylate; 2-Piperidin-4-yloxy-3-nitropyridine, 1-Boc protected; 1065484-06-1; 4-(3-Nitropyridin-2-yloxy)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-nitropyridin-2-yloxy)piperidine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support development needs from milligram to kilogram scale with a commitment to reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.