Description

Methyl 5-Amino-2-Iodobenzoate CAS NO 1065102-79-5 is a high-purity iodinated aromatic ester building block, valued for its dual functional groups that enable versatile synthetic transformations. This compound is critical for researchers and manufacturers requiring precise, high-quality intermediates for complex molecule construction. It is primarily utilized in the pharmaceutical and agrochemical sectors for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and photoactive materials due to its electron-rich aromatic system.
• Chemical Biology Probes: Acts as a starting point for synthesizing molecular probes and tags used in bio-conjugation and imaging studies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated intermediates.

Basic Information

Product Name	Methyl 5-Amino-2-Iodobenzoate
CAS No.	1065102-79-5
Molecular Formula	C8H8INO2
Molecular Weight	277.06 g/mol
Synonyms	Methyl 5-amino-2-iodobenzoate; 2-Iodo-5-aminobenzoic acid methyl ester; Benzoic acid, 5-amino-2-iodo-, methyl ester; 5-Amino-2-iodobenzoic acid methyl ester; Methyl 2-iodo-5-aminobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.