Description

tert-Butyl 4-((3-Bromo-2-Oxopyridin-1(2H)-Yl)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, neurology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in kinase inhibitor research.
• Medicinal Chemistry R&D: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for clients.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry Development: Acts as a critical intermediate during the scale-up and process optimization of API manufacturing routes.

Basic Information

Product Name	tert-Butyl 4-((3-Bromo-2-Oxopyridin-1(2H)-Yl)Methyl)Piperidine-1-Carboxylate
CAS No.	1065075-65-1
Molecular Formula	C16H21BrN2O3
Molecular Weight	369.26 g/mol
Synonyms	1-Boc-4-((3-bromo-2-oxopyridin-1(2H)-yl)methyl)piperidine; 1-(tert-Butoxycarbonyl)-4-((3-bromo-2-oxo-1,2-dihydropyridin-1-yl)methyl)piperidine; tert-Butyl 4-[(3-bromo-2-oxo-1,2-dihydropyridin-1-yl)methyl]piperidine-1-carboxylate; 4-((3-Bromo-2-oxopyridin-1(2H)-yl)methyl)piperidine-1-carboxylic acid tert-butyl ester; 1,2-Dihydro-3-bromo-1-[(1-(tert-butoxycarbonyl)-4-piperidinyl)methyl]-2-pyridinone; 1065075-65-1; tert-Butyl 4-((3-bromo-2-oxo-1,2-dihydropyridin-1-yl)methyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((3-Bromo-2-Oxopyridin-1(2H)-Yl)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.