Description

Methyl 4-Bromo-2-Chloronicotinate is a high-purity halogenated nicotinate derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its versatility as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries requiring precise and reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis: An essential building block for constructing complex heterocyclic compounds and for introducing functional groups via cross-coupling reactions (e.g., Suzuki, Stille).
• Academic & Industrial R&D: Employed in medicinal chemistry programs and process development for scale-up synthesis.

Basic Information

Product Name	Methyl 4-Bromo-2-Chloronicotinate
CAS No.	1064678-14-3
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	Methyl 4-bromo-2-chloropyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 4-bromo-2-chloro-, methyl ester; 4-Bromo-2-chloronicotinic acid methyl ester; 2-Chloro-4-bromonicotinic acid methyl ester; Methyl 2-chloro-4-bromonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2-Chloronicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.