Description

Methyl 2-Acetamido-3-(3-Pyridyl)Propanoate is a high-purity, non-natural amino acid derivative featuring a pyridyl side chain, serving as a critical chiral building block in advanced organic synthesis. Its value lies in enabling the precise construction of complex molecules for pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Peptidomimetics Construction: Used to incorporate non-natural amino acid residues into peptide analogs to enhance stability, bioavailability, and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of advanced active ingredients with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.

Basic Information

Product Name	Methyl 2-Acetamido-3-(3-Pyridyl)Propanoate
CAS No.	1064157-45-4
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	Methyl N-Acetyl-3-(3-pyridyl)-D/L-alaninate; 2-Acetamido-3-(3-pyridyl)propanoic Acid Methyl Ester; 3-Pyridylalanine Derivative; N-Acetyl-3-(3-pyridinyl)alanine Methyl Ester; Methyl (2-acetamido-3-pyridin-3-ylpropanoate); (RS)-Methyl 2-acetamido-3-(pyridin-3-yl)propanoate; 1064157-45-4; 3-Pyridyl Alanine Methyl Ester Acetamide
EINECS	Contact for details

Quality Control

Our Methyl 2-Acetamido-3-(3-Pyridyl)Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for research and non-GMP development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Specify D-, L-, or Racemic
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.