Description

6-Chloro-4-Iodo-Pyridin-2-Ylamine is a halogenated pyridine derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on the pyridine core, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Cross-Coupling Reactions: The iodo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used to synthesize molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	6-Chloro-4-Iodo-Pyridin-2-Ylamine
CAS No.	1062608-73-4
Molecular Formula	C5H4ClIN2
Molecular Weight	254.46 g/mol
Synonyms	2-Amino-6-chloro-4-iodopyridine; 4-Iodo-6-chloropyridin-2-amine; 6-Chloro-4-iodopyridin-2-amine; 2-Pyridinamine, 6-chloro-4-iodo-; (6-Chloro-4-iodopyridin-2-yl)amine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 6-Chloro-4-Iodo-Pyridin-2-Ylamine is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity, purity, and the absence of critical impurities. We adhere to strict in-process controls. Certificates of Analysis (COA) are available upon request and provide full traceability and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.