Description

6-Bromo-4-Iodonicotinonitrile is a high-value halogenated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both bromine and iodine substituents on the pyridine ring, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Negishi) due to the differential reactivity of its bromo and iodo groups.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and developing novel synthetic methodologies.
• Ligand and Catalyst Development: Useful for the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Bromo-4-Iodonicotinonitrile
CAS No.	1061357-87-6
Molecular Formula	C6H2BrIN2
Molecular Weight	308.90 g/mol
Synonyms	4-Iodo-6-bromonicotinonitrile; 6-Bromo-4-iodopyridine-3-carbonitrile; 3-Cyano-6-bromo-4-iodopyridine; Nicotinonitrile, 6-bromo-4-iodo-; 6-Bromo-4-iodo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Iodonicotinonitrile is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates, ensuring traceability and compliance for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.