Description

2,5-Dibromo-4-Iodopyridine is a highly functionalized halogenated pyridine derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its value lies in the strategic placement of three distinct halogen atoms, which allows for sequential, site-selective cross-coupling reactions to construct complex heterocyclic architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used to construct novel pyridine-based herbicides, fungicides, and insecticides with enhanced activity.
• Ligand and Catalyst Development: Serves as a scaffold for creating sophisticated polydentate ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems.
• Cross-Coupling Reactions: An ideal substrate for Suzuki, Stille, and Negishi couplings due to the differential reactivity of the bromine and iodine atoms.

Basic Information

Product Name	2,5-Dibromo-4-Iodopyridine
CAS No.	1061357-86-5
Molecular Formula	C5H2Br2IN
Molecular Weight	402.79 g/mol
Synonyms	4-Iodo-2,5-dibromopyridine; 2,5-Dibromo-4-iodopyridine; Pyridine, 2,5-dibromo-4-iodo-; 4-Iodo-2,5-dibromopyridine; 1061357-86-5; SCHEMBL21883027; BRN 1260505; AKOS025247213
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.