Description

6-Chloro-4-Iodopyridine-3-Carbonitrile is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex heterocyclic systems and functionalized molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Used in the research and production of advanced organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Research: A valuable reagent for academic and industrial R&D in medicinal and synthetic organic chemistry.

Basic Information

Product Name	6-Chloro-4-Iodopyridine-3-Carbonitrile
CAS No.	1061357-83-2
Molecular Formula	C6H2ClIN2
Molecular Weight	264.45 g/mol
Synonyms	3-Cyano-6-chloro-4-iodopyridine; 4-Iodo-6-chloropyridine-3-carbonitrile; 6-Chloro-4-iodonicotinonitrile; 6-Chloro-4-iodo-3-pyridinecarbonitrile; 6-Chloro-4-iodo-3-cyanopyridine; 4-Iodo-6-chloro-3-cyanopyridine; 3-Pyridinecarbonitrile, 6-chloro-4-iodo-
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Iodopyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.